Differentiation of endometrial stem cells into motor neurons by the use of purmorphamin small molecule

Background: Small molecule Purmorphamin (PMA) is the agonist of smoothened protein in Sonic hedgehog (Shh) signaling pathway. Effect of purmorphamin small molecule on differentiation of mesenchymal cells into bone tissue has been studied previously. Use of Shh causes progression of neural differenti...

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Bibliographic Details
Main Authors: Homa Mohseni Kouchesfahani, Somayeh Ebrahimi-Barough, Jafar Ai, Azam Rahimi
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2017-03-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5544&slc_lang=en&sid=1