Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry.

Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry.

The envelope glycoproteins of primate lentiviruses, including human and simian immunodeficiency viruses (HIV and SIV), are heterodimers of a transmembrane glycoprotein (usually gp41), and a surface glycoprotein (gp120), which binds CD4 on target cells to initiate viral entry. We have used electron t...

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Bibliographic Details
Main Authors: Rachid Sougrat, Alberto Bartesaghi, Jeffrey D Lifson, Adam E Bennett, Julian W Bess, Daniel J Zabransky, Sriram Subramaniam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030063

Internet

https://doi.org/10.1371/journal.ppat.0030063

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