Palindromic sequence artifacts generated during next generation sequencing library preparation from historic and ancient DNA.

Palindromic sequence artifacts generated during next generation sequencing library preparation from historic and ancient DNA.

Degradation-specific processes and variation in laboratory protocols can bias the DNA sequence composition from samples of ancient or historic origin. Here, we identify a novel artifact in sequences from historic samples of Atlantic cod (Gadus morhua), which forms interrupted palindromes consisting...

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Bibliographic Details
Main Authors: Bastiaan Star, Alexander J Nederbragt, Marianne H S Hansen, Morten Skage, Gregor D Gilfillan, Ian R Bradbury, Christophe Pampoulie, Nils Chr Stenseth, Kjetill S Jakobsen, Sissel Jentoft
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24608104/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24608104/?tool=EBI

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