Nox-2-mediated phenotype loss of hippocampal parvalbumin interneurons might contribute to postoperative cognitive decline in aging mice

Nox-2-mediated phenotype loss of hippocampal parvalbumin interneurons might contribute to postoperative cognitive decline in aging mice

Postoperative cognitive decline (POCD) is a common complication following anesthesia and surgery, especially in elderly patients; however, the precise mechanisms of POCD remain unclear. Here, we investigated whether nicotinamide adenine dinucleotide phosphate (NADPH) oxidase mediated-abnormalities i...

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Bibliographic Details
Main Authors: lili qiu, dan luo, hui zhang, yun s shi, yanjun li, dan wu, jiang chen, muhuo ji, Jianjun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Aging
Hippocampus
parvalbumin
NOX2
Apocynin
postoperative cognitive decline
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00234/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00234/full

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