Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging

<p>Abstract</p> <p>Background</p> <p>Temperature affects virtually all cellular processes. A quick increase in temperature challenges the cells to undergo a heat shock response to maintain cellular homeostasis. Heat shock factor-1 (HSF-1) functions as a major player in...

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Bibliographic Details
Main Authors: Barna János, Princz Andrea, Kosztelnik Mónika, Hargitai Balázs, Takács-Vellai Krisztina, Vellai Tibor
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Developmental Biology
Subjects:
Online Access:http://www.biomedcentral.com/1471-213X/12/32