Discovery of novel determinants of endothelial lineage using chimeric heterokaryons
We wish to identify determinants of endothelial lineage. Murine embryonic stem cells (mESC) were fused with human endothelial cells in stable, non-dividing, heterokaryons. Using RNA-seq, it is possible to discriminate between human and mouse transcripts in these chimeric heterokaryons. We observed a...
Main Authors: | Wing Tak Wong, Gianfranco Matrone, XiaoYu Tian, Simion Alin Tomoiaga, Kin Fai Au, Shu Meng, Sayumi Yamazoe, Daniel Sieveking, Kaifu Chen, David M Burns, James K Chen, Helen M Blau, John P Cooke |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/23588 |
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