Compartmentalization of stearoyl-coenzyme A desaturase 1 activity in HepG2 cells*

Stearoyl-coenzyme A desaturase 1 (SCD1) catalyzes the conversion of stearate (18:0) to oleate (18:1n-9) and of palmitate (16:0) to palmitoleate (16:1), which are key steps in triglyceride synthesis in the fatty acid metabolic network. This study investigated the role of SCD1 in fatty acid metabolism...

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Bibliographic Details
Main Authors: Jennifer K. Yee, Catherine S. Mao, Heidi S. Hummel, Shu Lim, Sharon Sugano, Virender K. Rehan, Gary Xiao, Wai-Nang Paul Lee
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346356