SPC-Cre-ERT2 transgenic mouse for temporal gene deletion in alveolar epithelial cells.

Although several Cre-loxP-based gene knockout mouse models have been generated for the study of gene function in alveolar epithelia in the lung, their applications are still limited. In this study, we developed a SPC-Cre-ER(T2) mouse model, in which a tamoxifen-inducible Cre recombinase (Cre-ER(T2))...

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Bibliographic Details
Main Authors: Yao-Song Gui, Lianmei Wang, Xinlun Tian, Ruie Feng, Aiping Ma, Baiqiang Cai, Hongbing Zhang, Kai-Feng Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457936?pdf=render