Effects of puerarin on the pharmacokinetics of astragaloside IV in rats and its potential mechanism

Effects of puerarin on the pharmacokinetics of astragaloside IV in rats and its potential mechanism

Context Puerarin and astragaloside IV (AS-IV) are sometimes used together for the treatment of disease in Chinese clinics, however, the drug–drug interaction between puerarin and AS-IV is still unknown. Objective This study investigates the effects of puerarin on the pharmacokinetics of astragalosid...

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Bibliographic Details
Main Authors: Huan Zhang, Jiaying Song, Huizhen Dai, Yanchao Liu, Lili Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
drug–drug interaction
cyp3a4
p-gp
metabolism
transport
Online Access:http://dx.doi.org/10.1080/13880209.2020.1746362

Internet

http://dx.doi.org/10.1080/13880209.2020.1746362

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