Methimazole-induced hypothyroidism causes alteration of the REDOX environment, oxidative stress, and hepatic damage; events not caused by hypothyroidism itself

Methimazole-induced hypothyroidism causes alteration of the REDOX environment, oxidative stress, and hepatic damage; events not caused by hypothyroidism itself

Our objective was to compare, over a time-course, markers of oxidative stress, the REDOX environment, and the antioxidant enzymatic system in the liver of rats with methimazole-or thyroidectomy-caused hypothyroidism.Methods. We used 60 male Wistar rats divided into four groups: 1) the euthyroid, whi...

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Bibliographic Details
Main Authors: Edgar Cano-Europa, Vanessa Blas-Valdivia, Gabriel Eduardo Lopez-Galindo, Margarita Franco-Colin, Marisol Pineda-Reynoso, Adelaida Hernandez-Garcia, Rocio Ortiz-Butron
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Annals of Hepatology
Subjects:
Antioxidant systems
Antithyroid drug
Liver
Reactive oxygen species
Thyroidectomy
Thyroid gland
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119316849

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http://www.sciencedirect.com/science/article/pii/S1665268119316849

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