Characterization of the distal promoter of the human pyruvate carboxylase gene in pancreatic beta cells.

Pyruvate carboxylase (PC) is an enzyme that plays a crucial role in many biosynthetic pathways in various tissues including glucose-stimulated insulin secretion. In the present study, we identify promoter usage of the human PC gene in pancreatic beta cells. The data show that in the human, two alter...

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Bibliographic Details
Main Authors: Ansaya Thonpho, Pinnara Rojvirat, Sarawut Jitrapakdee, Michael J MacDonald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3559343?pdf=render