Characteristics of Cohesin Mutation in Acute Myeloid Leukemia and Its Clinical Significance
The occurrence of gene mutation is a major contributor to the initiation and propagation of acute myeloid leukemia (AML). Accumulating evidence suggests that genes encoding cohesin subunits have a high prevalence of mutations in AML, especially in the t(8;21) subtype. Therefore, it is important to u...
Main Authors: | Caixia Han, Xuefeng Gao, Yonghui Li, Juan Zhang, Erna Yang, Li Zhang, Li Yu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-04-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2021.579881/full |
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