Subchronic Exposure to Arsenic Represses the TH/TRβ1-CaMK IV Signaling Pathway in Mouse Cerebellum

Subchronic Exposure to Arsenic Represses the TH/TRβ1-CaMK IV Signaling Pathway in Mouse Cerebellum

We previously reported that arsenic (As) impaired learning and memory by down-regulating calmodulin-dependent protein kinase IV (CaMK IV) in mouse cerebellum. It has been documented that the thyroid hormone receptor (TR)/retinoid X receptor (RXR) heterodimer and thyroid hormone (TH) may be involved...

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Bibliographic Details
Main Authors: Huai Guan, Shuangyue Li, Yanjie Guo, Xiaofeng Liu, Yi Yang, Jinqiu Guo, Sheng Li, Cong Zhang, Lixin Shang, Fengyuan Piao
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:International Journal of Molecular Sciences
Subjects:
arsenic
thyroid hormone receptor
CaMK IV
cerebellum
retinoid X receptor
Online Access:http://www.mdpi.com/1422-0067/17/2/157

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http://www.mdpi.com/1422-0067/17/2/157

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