T-Cell Mediated Immune Responses Induced in ret Transgenic Mouse Model of Malignant Melanoma

T-Cell Mediated Immune Responses Induced in ret Transgenic Mouse Model of Malignant Melanoma

Poor response of human malignant melanoma to currently available treatments requires a development of innovative therapeutic strategies. Their evaluation should be based on animal models that resemble human melanoma with respect to genetics, histopathology and clinical features. Here we used a trans...

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Bibliographic Details
Main Authors: Dirk Schadendorf, Viktor Umansky, Masashi Kato, Kathrin Frank, Wolfram Osen, Oliver Abschuetz
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Cancers
Subjects:
melanoma
transgenic mouse model
T cells
immunization, cytokines
melanoma associated antigens
Online Access:http://www.mdpi.com/2072-6694/4/2/490/

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http://www.mdpi.com/2072-6694/4/2/490/

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