Histological correlates of hippocampal magnetization transfer images in drug-resistant temporal lobe epilepsy patients

Histological correlates of hippocampal magnetization transfer images in drug-resistant temporal lobe epilepsy patients

Objective: Temporal lobe epilepsy patients (TLE) often present with hippocampal atrophy, increased T2 relaxation, and reduced magnetization transfer ratio (MTR) in magnetic resonance images (MRI). The histological correlates of the reduced hippocampal MTR are so far unknown. Since MTR is dependent o...

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Bibliographic Details
Main Authors: Jose Eduardo Peixoto-Santos, Tonicarlo R. Velasco, Carlos Gilberto Carlotti, Joao Alberto Assirati, Gustavo Henrique de Souza e Rezende, Katja Kobow, Roland Coras, Ingmar Blümcke, Carlos Ernesto Garrido Salmon, Antonio Carlos dos Santos, Joao Pereira Leite
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Temporal lobe epilepsy
Hippocampal sclerosis
Magnetization transfer ratio
Extracellular matrix
Neuron density
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303004

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http://www.sciencedirect.com/science/article/pii/S2213158220303004

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