Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features

Polyphenols exert beneficial effects in type 2 diabetes mellitus (T2DM). However, their mechanism of action remains largely unknown. Endothelial Akt-kinase plays a key role in the pathogenesis of cardiovascular complications in T2DM and therefore the modulation of its activity is of interest. This w...

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Bibliographic Details
Main Authors: Stoyan Dirimanov, Petra Högger
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/6/219