Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features
Polyphenols exert beneficial effects in type 2 diabetes mellitus (T2DM). However, their mechanism of action remains largely unknown. Endothelial Akt-kinase plays a key role in the pathogenesis of cardiovascular complications in T2DM and therefore the modulation of its activity is of interest. This w...
Main Authors: | Stoyan Dirimanov, Petra Högger |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-06-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/9/6/219 |
Similar Items
-
Fluorescence interference of polyphenols in assays screening for dipeptidyl peptidase IV inhibitory activity
by: Stoyan Dirimanov, et al.
Published: (2020-12-01) -
Selective Phosphorylation of Akt/Protein-Kinase B Isoforms in Response to Dietary Cues
by: Laura Christin Trautenberg, et al.
Published: (2019-10-01) -
AKT/GSK3 signaling pathways and schizophrenia
by: Effat eEmamian
Published: (2012-03-01) -
Identification of a RAC/AKT-like gene in Leishmania parasites as a putative therapeutic target in leishmaniasis
by: Rubén E. Varela-M, et al.
Published: (2017-10-01) -
Functional specificity of Akt isoforms in cancer progression
by: Fortier Anne-Marie, et al.
Published: (2011-04-01)