Endogenous fluorescence signatures in living pluripotent stem cells change with loss of potency.

The therapeutic potential of stem cells is limited by the non-uniformity of their phenotypic state. Thus it would be advantageous to noninvasively monitor stem cell status. Driven by this challenge, we employed multidimensional multiphoton microscopy to quantify changes in endogenous fluorescence oc...

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Bibliographic Details
Main Authors: Jayne M Squirrell, Jimmy J Fong, Carlos A Ariza, Amber Mael, Kassondra Meyer, Nirupama K Shevde, Avtar Roopra, Gary E Lyons, Timothy J Kamp, Kevin W Eliceiri, Brenda M Ogle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430704?pdf=render