ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Abstract Capture Hi-C (CHi-C) is a new technique for assessing genome organization based on chromosome conformation capture coupled to oligonucleotide capture of regions of interest, such as gene promoters. Chromatin loop detection is challenging because existing Hi-C/4C-like tools, which make diffe...

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Bibliographic Details
Main Authors: Yousra Ben Zouari, Anne M. Molitor, Natalia Sikorska, Vera Pancaldi, Tom Sexton
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Genome Biology
Subjects:
Promoter-enhancer interactions
Chromatin loops
Capture Hi-C
Biological replicates
Gene regulation
Chromatin assortativity
Online Access:http://link.springer.com/article/10.1186/s13059-019-1706-3

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http://link.springer.com/article/10.1186/s13059-019-1706-3

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