In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells.

In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells.

Excessive production of monoclonal light chains due to multiple myeloma can induce aggregation-related disorders, such as light chain amyloidosis (AL) and light chain deposition diseases (LCDD). In this work, we produce a non-amyloidogenic IgE λ light chain dimer from human mammalian cells U266, whi...

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Bibliographic Details
Main Authors: Paolo Arosio, Marta Owczarz, Thomas Müller-Späth, Paola Rognoni, Marten Beeg, Hua Wu, Mario Salmona, Massimo Morbidelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3303827?pdf=render

Internet

http://europepmc.org/articles/PMC3303827?pdf=render

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