Visualization of acute liver damage induced by cycloheximide in rats using PET with [(18)F]FEDAC, a radiotracer for translocator protein (18 kDa).

Liver damage induced by drug toxicity is an important concern for both medical doctors and patients. The aim of this study was to noninvasively visualize acute liver damage using positron emission tomography (PET) with N-benzyl-N-methyl-2-[7,8-dihydro-7-(2-[(18)F]fluoroethyl)-8-oxo-2-phenyl-9H-purin...

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Bibliographic Details
Main Authors: Akiko Hatori, Joji Yui, Lin Xie, Tomoteru Yamasaki, Katsushi Kumata, Masayuki Fujinaga, Hidekatsu Wakizaka, Masanao Ogawa, Nobuki Nengaki, Kazunori Kawamura, Ming-Rong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3900578?pdf=render