Clinicopathologic characterization and abnormal autophagy of CSF1R-related leukoencephalopathy

Clinicopathologic characterization and abnormal autophagy of CSF1R-related leukoencephalopathy

Abstract Background CSF1R-related leukoencephalopathy, also known as hereditary diffuse leukoencephalopathy with spheroids (HDLS), is a rare white-matter encephalopathy characterized by motor and neuropsychiatric symptoms due to colony-stimulating factor 1 receptor (CSF1R) gene mutation. Few of CSF1...

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Bibliographic Details
Main Authors: Wo-Tu Tian, Fei-Xia Zhan, Qing Liu, Xing-Hua Luan, Chao Zhang, Liang Shang, Ben-Yan Zhang, Si-Jian Pan, Fei Miao, Jiong Hu, Ping Zhong, Shi-Hua Liu, Ze-Yu Zhu, Hai-Yan Zhou, Suya Sun, Xiao-Li Liu, Xiao-Jun Huang, Jing-Wen Jiang, Jian-Fang Ma, Ying Wang, Shu-Fen Chen, Hui-Dong Tang, Sheng-Di Chen, Li Cao
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Translational Neurodegeneration
Subjects:
Hereditary diffuse leukoencephalopathy with spheroids
CSF1R
Autophagy
Haploinsufficiency
Online Access:https://doi.org/10.1186/s40035-019-0171-y

Internet

https://doi.org/10.1186/s40035-019-0171-y

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