Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors

Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors

Cell viability studies for benzo[1,2,4]triazin-7-ones and 1,2,4-benzotriazinyl (Blatter-type) radical precursors are described with comparisons made with 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO). All of the stable free radicals were several orders of magnitude less cytotoxic than the benzo[1,2,4...

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Bibliographic Details
Main Authors: Lee-Ann J. Keane, Styliana I. Mirallai, Martin Sweeney, Michael P. Carty, Georgia A. Zissimou, Andrey A. Berezin, Panayiotis A. Koutentis, Fawaz Aldabbagh
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
anti-tumour
blatter-type radical
heterocyclic compound
NCI
pleurotin
TEMPO
Online Access:http://www.mdpi.com/1420-3049/23/3/574

Internet

http://www.mdpi.com/1420-3049/23/3/574

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