Drug interaction between valproic acid and carbapenems in patients with epileptic seizures

Drug interaction between valproic acid and carbapenems in patients with epileptic seizures

Valproic acid (VPA) is a widely used antiepileptic drug (AED). When carbapenems are concomitantly used with VPA, the serum levels of VPA may decrease and aggravate seizures. The aim of this study was to evaluate the risk factors associated with decreased serum VPA levels and clinical outcome in pati...

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Bibliographic Details
Main Authors: Chi-Ren Huang, Chih-Hsiang Lin, Shu-Chen Hsiao, Nai-Ching Chen, Wan-Chen Tsai, Shang-Der Chen, Yan-Ting Lu, Yao-Chung Chuang
Format: Article
Language:English
Published: Wiley 2017-03-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Antiepileptic drugs
Carbapenems
Drug interaction
Epileptic seizures
Valproic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X16304715

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http://www.sciencedirect.com/science/article/pii/S1607551X16304715

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