Endothelin-1 stimulates human monocytes in vitro to release TNF-α , IL-1β and IL-6
Increased plasma- and tissue levels of endothelin-1 (ET-1) during inflammatory diseases, have suggested a role of ET-1 in the pathophysiology of inflammatory reactions. The authors have studied the effect of ET-1 on cytokine release from monocytes and monocyte-derived macrophages. ET-1 increased sec...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
1993-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935193000596 |