Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7

Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7

ABSTRACT BACKGROUND Dengue fever may present hemorrhages and cavitary effusions as result of exacerbated immune responses. We investigated hydro-alcoholic extracts from leaves (UGL) and bark (UGB) of the medicinal species Uncaria guinanensis with respect to antiviral effects in Dengue virus (DENV)...

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Bibliographic Details
Main Authors: Cíntia da Silva Mello, Ligia Maria Marino Valente, Thiago Wolff, Raimundo Sousa Lima-Junior, Luciana Gomes Fialho, Cintia Ferreira Marinho, Elzinandes Leal Azeredo, Luzia Maria Oliveira-Pinto, Rita de Cássia Alves Pereira, Antonio Carlos Siani, Claire Fernandes Kubelka
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
dengue
Uncaria guianensis
traditional medicine
immunomodulation
antivirals
kaempferitrin
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000600458&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000600458&lng=en&tlng=en

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