Effect of Chitosan Coating on PLGA Nanoparticles for Oral Delivery of Thymoquinone: In Vitro, Ex Vivo, and Cancer Cell Line Assessments

In the present study, thymoquinone (TQ)-encapsulated chitosan- (CS)-coated poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles (NPs) were formulated using the emulsion evaporation method. NPs were optimized by using 3<sup>3</sup>-QbD approach for improved efficacy against breast cancer....

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Bibliographic Details
Main Authors: Sultan Alshehri, Syed Sarim Imam, Md. Rizwanullah, Khalid Umar Fakhri, Mohd. Moshahid Alam Rizvi, Wael Mahdi, Mohsin Kazi
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Coatings
Subjects:
Online Access:https://www.mdpi.com/2079-6412/11/1/6