Prune-1 drives polarization of tumor-associated macrophages (TAMs) within the lung metastatic niche in triple-negative breast cancer

Prune-1 drives polarization of tumor-associated macrophages (TAMs) within the lung metastatic niche in triple-negative breast cancer

Summary: M2-tumor-associated macrophages (M2-TAMs) in the tumor microenvironment represent a prognostic indicator for poor outcome in triple-negative breast cancer (TNBC).Here we show that Prune-1 overexpression in human TNBC patients has positive correlation to lung metastasis and infiltrating M2-T...

Full description

Bibliographic Details
Main Authors: Veronica Ferrucci, Fatemeh Asadzadeh, Francesca Collina, Roberto Siciliano, Angelo Boccia, Laura Marrone, Daniela Spano, Marianeve Carotenuto, Cristina Maria Chiarolla, Daniela De Martino, Gennaro De Vita, Alessandra Macrì, Luisa Dassi, Jonathan Vandenbussche, Natascia Marino, Monica Cantile, Giovanni Paolella, Francesco D'Andrea, Maurizio di Bonito, Kris Gevaert, Massimo Zollo
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Molecular Biology
Immunology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311354

Internet

http://www.sciencedirect.com/science/article/pii/S2589004220311354

Similar Items