Multiple proteins arising from a single gene: The role of the Spa33 variants in Shigella T3SS regulation

Multiple proteins arising from a single gene: The role of the Spa33 variants in Shigella T3SS regulation

Abstract Shigella invasion and dissemination in intestinal epithelial cells relies on a type 3 secretion system (T3SS), which mediates translocation of virulence proteins into host cells. T3SSs are composed of three major parts: an extracellular needle, a basal body, and a cytoplasmic complex. Three...

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Bibliographic Details
Main Authors: Mahendar Kadari, Dalila Lakhloufi, Valérie Delforge, Virginie Imbault, David Communi, Pierre Smeesters, Anne Botteaux
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:MicrobiologyOpen
Subjects:
bacterial virulence
pathogenesis
secretion regulation
Shigella flexneri
type 3 secretion system
Online Access:https://doi.org/10.1002/mbo3.932

Internet

https://doi.org/10.1002/mbo3.932

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