HPP and SGQR peptides from silkworm pupae protein hydrolysates regulated biosynthesis of cholesterol in HepG2 cell line

HPP and SGQR peptides from silkworm pupae protein hydrolysates regulated biosynthesis of cholesterol in HepG2 cell line

To screen several peptides that could possibly inhibit the biosynthesis of cholesterol, we selected peptides with high 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMGCR) inhibitory activity from silkworm pupae protein hydrolysates (SPPHs). SPPH was obtained by hydrolysing the proteins with neu...

Full description

Bibliographic Details
Main Authors: Suling Sun, Wei Wang, Nan Wang, Yu Zhang, Zuoyi Zhu, Xue Li, Junhong Wang, Qihe Chen, Faizan Ahmed Sadiq, Hua Yang, Qianhui Qi, Guohua Zhang
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Functional Foods
Subjects:
His-Pro-Pro
Ser-Gly-Gln-Arg
Silkworm pupae
3-Hydroxy-3-methyl glutaryl coenzyme A reductase
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620305521

Internet

http://www.sciencedirect.com/science/article/pii/S1756464620305521

Similar Items