Retinoic acid metabolic genes, meiosis, and gonadal sex differentiation in zebrafish.

To help understand the elusive mechanisms of zebrafish sex determination, we studied the genetic machinery regulating production and breakdown of retinoic acid (RA) during the onset of meiosis in gonadogenesis. Results uncovered unexpected mechanistic differences between zebrafish and mammals. Conse...

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Bibliographic Details
Main Authors: Adriana Rodríguez-Marí, Cristian Cañestro, Ruth A BreMiller, Julian M Catchen, Yi-Lin Yan, John H Postlethwait
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769385?pdf=render