Choline Deficiency Attenuates Body Weight Gain and Improves Glucose Tolerance in ob/ob Mice

Previous studies demonstrated that choline supply is directly linked to high-fat-diet-induced obesity and insulin resistance in mice. The aim of this study was to evaluate if choline supply could also modulate obesity and insulin resistance caused by a genetic defect. Eight-week-old male ob/ob mice...

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Bibliographic Details
Main Authors: Gengshu Wu, Liyan Zhang, Tete Li, Gary Lopaschuk, Dennis E. Vance, René L. Jacobs
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2012/319172