PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT

PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT

Abstract Background Golgi Membrane Protein 1 (GOLM1), a protein involved in the trafficking of proteins through the Golgi apparatus, has been shown to be oncogenic in a variety of human cancers. Here, we examined the role of GOLM1 in the development of human glioma. Methods qRT-PCR, immunohistochemi...

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Bibliographic Details
Main Authors: Ran Xu, Jianxiong Ji, Xin Zhang, Mingzhi Han, Chao Zhang, Yangyang Xu, Yuzhen Wei, Shuai Wang, Bin Huang, Anjing Chen, Di Zhang, Qing Zhang, Wenjie Li, Zheng Jiang, Jian Wang, Xingang Li
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
AKT
GOLM1
Glioma
PDGFA
Progression
Online Access:http://link.springer.com/article/10.1186/s13046-017-0665-3

Internet

http://link.springer.com/article/10.1186/s13046-017-0665-3

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