Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation.

Congenital cytomegalovirus infections are a leading cause of neurodevelopmental disorders in human and represent a major health care and socio-economical burden. In contrast with this medical importance, the pathophysiological events remain poorly known. Murine models of brain cytomegalovirus infect...

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Main Authors: Robin Cloarec, Sylvian Bauer, Hervé Luche, Emmanuelle Buhler, Emilie Pallesi-Pocachard, Manal Salmi, Sandra Courtens, Annick Massacrier, Pierre Grenot, Natacha Teissier, Françoise Watrin, Fabienne Schaller, Homa Adle-Biassette, Pierre Gressens, Marie Malissen, Thomas Stamminger, Daniel N Streblow, Nadine Bruneau, Pierre Szepetowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4966896?pdf=render