ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility

ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility

Angiotensin-converting enzyme-2 (ACE2) receptor has been identified as the key adhesion molecule for the transmission of the SARS-CoV-2. However, there is no evidence that human genetic variation in ACE2 is singularly responsible for COVID-19 susceptibility. Therefore, we performed an integrative mu...

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Bibliographic Details
Main Authors: Gita A. Pathak, Frank R. Wendt, Aranyak Goswami, Dora Koller, Flavio De Angelis, COVID-19 Host Genetics Initiative, Renato Polimanti
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
ACE2
COVID-19
miRNA
immune response
network
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.698033/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.698033/full

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