Burkholderia pseudomallei Evades Nramp1 (Slc11a1)- and NADPH Oxidase-Mediated Killing in Macrophages and Exhibits Nramp1-Dependent Virulence Gene Expression

Burkholderia pseudomallei Evades Nramp1 (Slc11a1)- and NADPH Oxidase-Mediated Killing in Macrophages and Exhibits Nramp1-Dependent Virulence Gene Expression

Bacterial survival in macrophages can be affected by the natural resistance-associated macrophage protein 1 (Nramp1; also known as solute carrier family 11 member a1 or Slc11a1) which localizes to phagosome membranes and transports divalent cations, including iron. Little is known about the role of...

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Bibliographic Details
Main Authors: Veerachat Muangsombut, Patoo Withatanung, Varintip Srinon, Narisara Chantratita, Mark P. Stevens, Jenefer M. Blackwell, Sunee Korbsrisate
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
B. pseudomallei
B. thailandensis
iron
macrophages
Nramp1
Slc11a1
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00350/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00350/full

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