A Novel DNA Methylation Signature as an Independent Prognostic Factor in Muscle-Invasive Bladder Cancer

A Novel DNA Methylation Signature as an Independent Prognostic Factor in Muscle-Invasive Bladder Cancer

BackgroundMuscle-invasive bladder cancer (MIBC) accounts for approximately 20% of all urothelial bladder carcinomas (UBC) at time of diagnosis, and up to 30% of patients with non-muscle invasive UBC will progress to MIBC over time. An increasing body of evidence has revealed a strong correlation bet...

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Bibliographic Details
Main Authors: Zhijie Xu, Hemant Gujar, Guanghou Fu, Hamed Ahmadi, Sumeet Bhanvadia, Daniel J. Weisenberger, Baiye Jin, Parkash S. Gill, Inderbir Gill, Siamak Daneshmand, Kimberly D. Siegmund, Gangning Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
methylation and prognosis
bladder cancer (BC)
survival analysis
MIBC
ROC
DNA methylation marker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.614927/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.614927/full

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