Promoter Methylation of LEP and LEPR before and after Bariatric Surgery: A Cross-Sectional Study

Introduction: DNA methylation constitutes one important epigenetic mechanism that regulates gene expression in human cells. With regard to obesity, bariatric surgery-induced weight loss has been associated with promoter methylation changes in several genes. Hyperleptinemia is a characteristic featur...

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Bibliographic Details
Main Authors: Julia Wilhelm, Anna Birkenstock, Vanessa Buchholz, Astrid Müller, Sherif Adel Aly, Kerstin Gruner-Labitzke, Hinrich Koehler, Ralf Lichtinghagen, Kirsten Jahn, Adrian Groh, Kai G. Kahl, Martina de Zwaan, Thomas Hillemacher, Stefan Bleich, Helge Frieling
Format: Article
Language:English
Published: Karger Publishers 2021-02-01
Series:Obesity Facts
Subjects:
Online Access:https://www.karger.com/Article/FullText/511918