Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes
The adverse effects to humans and environment of only few chemicals are well known. Absorption, distribution, metabolism and excretion (ADME) are the steps of pharmaco/toxicokinetics that determine the internal dose of chemicals to which the organism is exposed. Of all the xenobiotic-metabolizing en...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-06-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00123/full |