Telomere-independent functions of telomerase in nuclei, cytoplasm and mitochondria
Telomerase canonical activity at telomeres prevents telomere shortening, allowing chromosome stability and cellular proliferation. To perform this task, the catalytic subunit (TERT) of the enzyme works as a reverse transcriptase together with the telomerase RNA component (TERC), adding telomeric rep...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-09-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00133/full |