Obesity and Low-Grade Inflammation Increase Plasma Follistatin-Like 3 in Humans

Background. Rodent models suggest that follistatin-like 3 (fstl3) is associated with diabetes and obesity. In humans, plasma fstl3 is reduced with gestational diabetes. In vitro, TNF-α induces fstl3 secretion, which suggests a link to inflammation. Objective. To elucidate the association between pla...

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Bibliographic Details
Main Authors: Claus Brandt, Maria Pedersen, Anders Rinnov, Anne S. Andreasen, Kirsten Møller, Pernille Hojman, Bente K. Pedersen, Peter Plomgaard
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/364209