Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the livers⃞

Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the livers⃞

Glucose disposal induces a signal that modulates the transcriptional regulation of genes involved in the glycolysis and lipogenesis pathways. To investigate the role of glucose metabolism on hepatic gene expression independently from insulin action, we overexpressed glucokinase, the limiting enzyme...

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Bibliographic Details
Main Authors: Núria Morral, Howard J. Edenberg, Scott R. Witting, Jennifer Altomonte, Tearina Chu, Matthew Brown
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
gene expression
hepatic steatosis
glucokinase
microarray analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425349

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http://www.sciencedirect.com/science/article/pii/S0022227520425349

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