Combinatorial pattern discovery approach for the folding trajectory analysis of a beta-hairpin.

The study of protein folding mechanisms continues to be one of the most challenging problems in computational biology. Currently, the protein folding mechanism is often characterized by calculating the free energy landscape versus various reaction coordinates, such as the fraction of native contacts...

Full description

Bibliographic Details
Main Authors: Laxmi Parida, Ruhong Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1183514?pdf=render