Presecretory degradation of apolipoprotein[a] is mediated by the proteasome pathway

Plasma levels of atherogenic lipoprotein [a] (Lp[a]) vary over a 1000-fold range and are largely determined by the gene for its unique glycoprotein, apolipoprotein [a] (apo[a]). The apo[a] locus comprises more than 100 alleles, encoding proteins from <300 to >800 kDa. Using primary baboon hepa...

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Bibliographic Details
Main Authors: Ann L. White, Bernadette Guerra, Jin Wang, Robert E. Lanford
Format: Article
Language:English
Published: Elsevier 1999-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520333678