Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress

Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress

Cisplatin is extensively used and is highly effective in clinical oncology; nevertheless, nephrotoxicity has severely limited its widespread utility. Isoquercitrin (IQC), a natural flavonoid widely found in herbage, is well known and recognized for its antioxidant, anti-inflammatory, and anti-apopto...

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Bibliographic Details
Main Authors: Hao Wang, Weiwei Xia, Guangfeng Long, Zhiyin Pei, Yuanyuan Li, Mengying Wu, Qian Wang, Yue Zhang, Zhanjun Jia, Hongbing Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
isoquercitrin
cisplatin
nephrotoxicity
apoptosis
inflammation
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.599416/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.599416/full

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