Antigen capsid-display on human adenovirus 35 via pIX fusion is a potent vaccine platform.

Durable protection against complex pathogens is likely to require immunity that comprises both humoral and cellular responses. While heterologous prime-boost regimens based on recombinant, replication-incompetent Adenoviral vectors (AdV) and adjuvanted protein have been able to induce high levels of...

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Bibliographic Details
Main Authors: Nadine C Salisch, Marija Vujadinovic, Esmeralda van der Helm, Dirk Spek, Lars Vorthoren, Jan Serroyen, Harmjan Kuipers, Hanneke Schuitemaker, Roland Zahn, Jerome Custers, Jort Vellinga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5375148?pdf=render