Involvement of Epigenetic Mechanisms in the Regulation of Secreted Phospholipase A2 Expressions in Jurkat Leukemia Cells

Epigenetic changes provide a frequent mechanism for transcriptional silencing of genes in cancer cells. We previously established that epigenetic mechanisms are important for control of group IIA phospholipase A2 (PLA2G2A) gene transcription in human DU-145 prostate cells. In this study, we analyze...

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Bibliographic Details
Main Authors: Mario Menschikowski, Albert Hagelgans, Heike Kostka, Graeme Eisenhofer, Gabriele Siegert
Format: Article
Language:English
Published: Elsevier 2008-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800164