Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3

Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3

<p>Abstract</p> <p>Background</p> <p>Extravasation of circulating cancer cells is a key event of metastatic dissemination that is initiated by the adhesion of cancer cells to endothelial cells. It requires interactions between adhesion receptors on endothelial cells and...

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Bibliographic Details
Main Authors: Paquet Éric R, Tremblay Pierre-Luc, Gout Stéphanie, Pin Anne-Laure, Houle François, Poirier Andrée, Porquet Nicolas, Klinck Roscoe, Auger François A, Huot Jacques
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Cancer
Subjects:
Death receptor-3
E-selectin
colon cancer
PI3 kinase
splice variant
Online Access:http://www.biomedcentral.com/1471-2407/11/285

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http://www.biomedcentral.com/1471-2407/11/285

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