Exposure to elevated glucose concentrations alters the metabolomic profile of bovine blastocysts.

Exposure to elevated glucose concentrations alters the metabolomic profile of bovine blastocysts.

Chronically high blood glucose concentrations are a characteristic of diabetes mellitus. Maternal diabetes affects the metabolism of early embryos and can cause a delay in development. To mimic maternal diabetes, bovine in vitro fertilization and embryo culture were performed in fertilization medium...

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Bibliographic Details
Main Authors: Karen Uhde, Helena T A van Tol, Tom A E Stout, Bernard A J Roelen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6010268?pdf=render

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http://europepmc.org/articles/PMC6010268?pdf=render

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