Syndecan-4 Modulates Cell Polarity and Migration by Influencing Centrosome Positioning and Intracellular Calcium Distribution

Efficient cell migration requires cellular polarization, which is characterized by the formation of leading and trailing edges, appropriate positioning of the nucleus and reorientation of the Golgi apparatus and centrosomes toward the leading edge. Migration also requires the development of an asymm...

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Main Authors: Daniel Becsky, Kitti Szabo, Szuzina Gyulai-Nagy, Tamas Gajdos, Zsuzsa Bartos, Arpad Balind, Laszlo Dux, Peter Horvath, Miklos Erdelyi, Laszlo Homolya, Aniko Keller-Pinter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.575227/full